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The characteristics of ethylene glycol and propylene glycol can be compared as
| Property | Ethylene Glycol | Propylene Glycol | Comments |
| Freeze point depression | more effective | less effective | More antifreeze is needed of propylene glycol to achieve the same freeze point |
| Heat transfer efficiency | less | better | Ethylene glycol can't carry as much heat as propylene glycol. More fluid must be circulated to transfer the same amount of energy. Pumps volume increased. |
| Viscosity | lower | higher | Propylene glycol increases major head loss in the systems. Pumps head increased. |
| Flammability | low | low | |
| Chemical oxygen demand | low | higher | |
| Biodegrading | degrades in 10 - 30 days | needs more than 20 - 30 days to degrade | |
| Carcinogenic | no | no | A carcinogen is any substance or agent that promotes cancer |
| Toxic | High level of acute when taken orally, targets the kidneys | Lower level of acute | Ethylene glycol should never be used in any drinking water or food processing system |
| Skin irritant | low | low | Propylene glycol is used in small amounts in cosmetics |
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